Renal function assessment in older people: comparative analysis of estimation equation with serum creatinine.

ABSTRACT:

Introduction

Age-related changes occurring in the kidney can lead to a reduction in Glomerular Filtration Rate (GFR); especially in older adults with multimorbidity and/or frailty, an accurate evaluation of kidney function is critical. For the estimation of GFR in patients over 70 years, CKD-EPI (Chronic Kidney Disease Epidemiology Collaboration) is often used. However, validated equations exist for old-age populations like BIS1 (Berlin Initiative Study 1) and FAS (Full Age Spectrum). Here we aimed to compare the performance of CKD-EPI, MDRD (Modification of Diet in Renal Disease), BIS1, and FAS in assessing eGFR in a population of patients over 70, to evaluate which equations show the most accurate performance in our setting.

Materials and methods

A total of 499 older adult

SUBMITTER: Peruzzo S 

PROVIDER: S-EPMC11652175 | biostudies-literature | 2024

REPOSITORIES: biostudies-literature