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Combining multiple stressors blocks bacterial migration and growth.

ABSTRACT: In nature, organisms experience combinations of stressors. However, laboratory studies use batch cultures, which simplify reality and focus on population-level responses to individual stressors.¹^,²^,³^,⁴^,⁵ In recent years, bacterial stress responses have been examined with single-cell resolution using microfluidics.⁶^,⁷^,⁸^,⁹^,¹⁰^,¹¹^,¹² Here, we use a microfluidic approach to simultaneously provide a physical stressor (shear flow) and a chemical stressor (H₂O₂) to the human pathogen Pseudomonas aeruginosa. By treating cells with levels o

SUBMITTER: Sharma A

PROVIDER: S-EPMC11652226 | biostudies-literature | 2024 Dec

REPOSITORIES: biostudies-literature

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Combining multiple stressors blocks bacterial migration and growth.

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