Comparison of outcomes between anticoagulation and antiplatelet therapies for intracranial arterial dissections.

ABSTRACT:

Background

This study aimed to evaluate real-world data on the differences in outcomes between antiplatelet (AP) and anticoagulation (AC) therapies for intracranial arterial dissection (IAD).

Methods

This study included patients with symptomatic unruptured IAD between 2010 and 2021 that were treated with anti-thrombotics. Patients were dichotomized to AC and AP based on a treatment policy analysis. Primary endpoints were a composite of ischemic early neurological deterioration, recurrent ischemic or hemorrhagic stroke, or 3-month mortality. Arterial changes were evaluated both in the early (during admission) and late (after discharge) periods. A treatment effectiveness analysis was also performed with AC, AP and a third group of antithrombotic cross-overs. Propensity score m

SUBMITTER: Lee SJ 

PROVIDER: S-EPMC11652506 | biostudies-literature | 2024

REPOSITORIES: biostudies-literature