Maternal organokines throughout pregnancy as predictors of neonatal anthropometric characteristics and adiposity.

ABSTRACT:

Aims

To evaluate the relation between maternal concentrations of progranulin (PGRN), adipocyte fatty acid-binding protein (AFABP), brain-derived neurotrophic factor (BDNF), and fibroblast growth factor 21 (FGF21) throughout pregnancy with neonatal weight and length at birth and at one month of age, as well as with the percentage of fat mass at one month of age. Besides, we evaluated the association between maternal organokine concentrations with pregestational nutritional status and gestational weight gain (GWG).

Methods

Longitudinal study of 100 healthy pregnant women and their neonates. Conventional biochemical tests were performed and maternal organokine concentrations were measured by ELISA. Neonatal percent fat mass was determined using the PEA POD system, and weight an

SUBMITTER: Valencia-Ortega J 

PROVIDER: S-EPMC11653021 | biostudies-literature | 2024

REPOSITORIES: biostudies-literature