Hippocampal Discoveries: Spatial View Cells, Connectivity, and Computations for Memory and Navigation, in Primates Including Humans.

ABSTRACT: Two key series of discoveries about the hippocampus are described. One is the discovery of hippocampal spatial view cells in primates. This discovery opens the way to a much better understanding of human episodic memory, for episodic memory prototypically involves a memory of where people or objects or rewards have been seen in locations "out there" which could never be implemented by the place cells that encode the location of a rat or mouse. Further, spatial view cells are valuable for navigation using vision and viewed landmarks, and provide for much richer, vision-based, navigation than the place to place self-motion update performed by rats and mice who live in dark underground tunnels. Spatial view cells thus offer a revolution in our understanding of the functions of the hippocampus

SUBMITTER: Rolls ET 

PROVIDER: S-EPMC11653063 | biostudies-literature | 2025 Jan

REPOSITORIES: biostudies-literature