Impact of Clinical Characteristics and Treatment on Cholangiocarcinoma Prognosis in Southern Thailand.

ABSTRACT:

Background

Cholangiocarcinoma (CCA) is most commonly seen in Northeastern Thailand and other parts of Asia where liver flukes are prevalent. However, it is unknown whether CCA patients in low and high liver fluke prevalence areas are similar. This study aimed to analyze the clinical characteristics and outcomes of CCA patients in Southern Thailand.

Methods

We retrospectively reviewed 223 patients diagnosed with CCA between 2018 and 2021 in a tertiary-care center. Clinicopathologic data were reviewed and compared between intrahepatic, perihilar, and distal CCA (iCCA, pCCA, and dCCA, respectively). Overall survivals (OS) were determined by Kaplan-Meier method and multivariable Cox regressions.

Results

The mean age was 63.9 years; 50.7% were men. The most common subtype

SUBMITTER: Sathitruangsak C 

PROVIDER: S-EPMC11653158 | biostudies-literature | 2024 Dec

REPOSITORIES: biostudies-literature