<i>Asparagus officinalis</i> L. extract exhibits anti-proliferative and anti-invasive effects in endometrial cancer cells and a transgenic mouse model of endometrial cancer.

ABSTRACT:

Introduction

Endometrial cancer is the most common malignancy of the female reproductive system in the United States. Asparagus officinalis is a versatile, nutrient-dense, low-calorie vegetable that contains various bioactive metabolites that have shown a variety of biologic functions beneficial to health. The metabolites from asparagus officinalis extracts or asparagus officinalis extracts exhibit significant anti-tumorigenic activity in some pre-clinical models of cancer.

Methods

Endometrial cancer cells were used to study the effects of asparagus officinalis on anti-proliferation, anti-invasion and increased sensitivity to cisplatin, and obese and lean Lkb1 ^fl/fl p53 ^fl/fl mouse model of endomet

SUBMITTER: Fang Z 

PROVIDER: S-EPMC11653357 | biostudies-literature | 2024

REPOSITORIES: biostudies-literature