Altered amino and fatty acids metabolism in Sudanese prostate cancer patients: insights from metabolic analysis.

ABSTRACT:

Introduction

Prostate cancer (PCa) management presents a multifaceted clinical challenge, intricately linking oncological considerations with cardiovascular health. Despite the recognized importance of lipid metabolism and hypertension in this interwoven relationship, their involvement in PCa development remains partially understood. This study aimed to explore variations in plasma metabolome among Sudanese PCa patients and their associated comorbidities.

Methods

Plasma samples were collected from 50 patients across four hospitals in Sudan and profiled by nuclear magnetic resonance (NMR) spectroscopy. One-dimensional proton NMR spectra were acquired for each sample using standard nuclear Overhauser effect spectroscopy pulse sequence presat on a 500 MHz Bruker Avance III HD N

SUBMITTER: Ahmed D 

PROVIDER: S-EPMC11653783 | biostudies-literature | 2024 Jan-Dec

REPOSITORIES: biostudies-literature