Clinical characteristics of patients requiring emergency hospitalization due to immune-related adverse events: a retrospective study.

ABSTRACT:

Background

Immune checkpoint inhibitors (ICIs) have revolutionized cancer treatment, offering hope for various malignancies by enhancing the immune response against tumors. However, ICIs are associated with unique immune-related adverse events (irAEs), which differ significantly from conventional chemotherapy-induced toxicities. These irAEs, which affect more than 70% of patients and often escalate to severe grades, present substantial clinical management challenges and frequently necessitate emergency hospitalization. Therefore, this study aimed to investigate the clinical characteristics of patients requiring emergency hospitalization due to irAEs during ICI therapy to enhance understanding and improve management strategies.

Methods

This retrospective study evaluated patie

SUBMITTER: Ikeda T 

PROVIDER: S-EPMC11653787 | biostudies-literature | 2024 Dec

REPOSITORIES: biostudies-literature