Near telomere-to-telomere genome assembly of Mongolian cattle: implications for population genetic variation and beef quality.

ABSTRACT:

Background

Mongolian cattle, a unique breed indigenous to China, represent valuable genetic resources and serve as important sources of meat and milk. However, there is a lack of high-quality genomes in cattle, which limits biological research and breeding improvement.

Findings

In this study, we conducted whole-genome sequencing on a Mongolian bull. This effort yielded a 3.1 Gb Mongolian cattle genome sequence, with a BUSCO integrity assessment of 95.9%. The assembly achieved both contig N50 and scaffold N50 values of 110.9 Mb, with only 3 gaps identified across the entire genome. Additionally, we successfully assembled the Y chromosome among the 31 chromosomes. Notably, 3 chromosomes were identified as having telomeres at both ends. The annotation data include 54.31% repeti

SUBMITTER: Su R 

PROVIDER: S-EPMC11653892 | biostudies-literature | 2024 Jan

REPOSITORIES: biostudies-literature