Biological links between psychological factors and adolescent depression: childhood trauma, rumination, and resilience.

ABSTRACT:

Background

The psychosocial factors play an important role in the development of depression in adolescents. we used metabolomics techniques to explore the links among childhood trauma, rumination, resilience, and adolescent depression.

Methods

We selected 57 adolescent depression patients and 53 healthy adolescents. The Childhood Trauma Questionnaire (CTQ), Hamilton Depression Scale (HAMD), Resilience Scale (CD-RISC), and Redundant Thinking Response Scale (RRS) were employed for the purpose of psychological assessment. The patients were regrouped according to their scores using the 27% high-low grouping method. Blood specimens were collected from all adolescents and metabolic data were obtained using LC-MS.

Results

We found no statistically significant difference betw

SUBMITTER: Guo X 

PROVIDER: S-EPMC11653987 | biostudies-literature | 2024 Dec

REPOSITORIES: biostudies-literature