Long-term chronic infection of a young immunocompromised patient by the SARS-CoV-2 P.2 VOI.

ABSTRACT: An immunocompromised patient was infected by the SARS-CoV-2 variant of interest named Zeta (P.2) in February 2021. More than one year later, he suffered from symptomatic COVID-19 and sequencing revealed the same variant, which accumulated 23 substitutions. This case illustrates intra-host evolution of a particular SARS-CoV-2 variant, highlighting the importance of genomic surveillance of immunocompromised patients.

SUBMITTER: Romano CM 

PROVIDER: S-EPMC11654138 | biostudies-literature | 2024

REPOSITORIES: biostudies-literature