Association between choroid plexus volume and cognitive function in community-dwelling older adults without dementia: a population-based cross-sectional analysis.

ABSTRACT:

Background

An increase in choroid plexus (CP) volume may be associated with cognitive decline in older individuals without dementia. In this study, we aimed to clarify whether CP volume can serve as an imaging marker of cognitive decline, determine how strongly CP volume is associated with cognitive decline, and explore factors associated with CP volume in older adults.

Methods

We measured CP volume, brain parenchyma, and cerebrospinal fluid (CSF) spaces associated with disproportionately enlarged subarachnoid space hydrocephalus (DESH), an imaging feature of normal-pressure hydrocephalus, in community-dwelling older adults aged ≥ 65 years without dementia.

Results

In 1,370 participants, lower Mini-Mental State Examination (MMSE) scores were significantly associated w

SUBMITTER: Hidaka Y 

PROVIDER: S-EPMC11654186 | biostudies-literature | 2024 Dec

REPOSITORIES: biostudies-literature