Long-term impact of maternal pre-pregnancy BMI on the risk of overweight/obesity in preschool children: mediation by infant birth weight and BMI trajectory group from 0 to 2 years.

ABSTRACT:

Background

Obesity is a complex multisystem disease that affects almost every organ system. Studying the early determinants of obesity and implementing targeted interventions have positive implications for promoting long-term health. Therefore, this study was to evaluate the impact of maternal pre-pregnancy overweight or obesity, weight gain rate (WGR) during the second and third trimesters, infant birth weight (IBW) and BMI trajectory group (BMI-TG) from 0 to 2 years on overweight or obesity in preschool children.

Methods

A retrospective cohort analysis of data obtained from a hospital was performed using chain-mediated effects to analyze the direct and indirect effects of prepregnancy body mass index (ppBMI)on preschool children's body mass index (pcBMI), and mediated by t

SUBMITTER: Mao A 

PROVIDER: S-EPMC11654201 | biostudies-literature | 2024 Dec

REPOSITORIES: biostudies-literature