Assessing readiness to use electronic health record data for outcome ascertainment in clinical trials - A case study.

ABSTRACT:

Background

Variable data quality poses a challenge to using electronic health record (EHR) data to ascertain acute clinical outcomes in multi-site clinical trials. Differing EHR platforms and data comprehensiveness across clinical trial sites, especially if patients received care outside of the clinical site's network, can also affect validity of results. Overcoming these challenges requires a structured approach.

Methods

We propose a framework and create a checklist to assess the readiness of clinical sites to contribute EHR data to a clinical trial for the purpose of outcome ascertainment, based on our experience with the Strategies to Reduce Injuries and Develop Confidence in Elders (STRIDE) study, which enrolled 5451 participants in 86 primary care practices across 10 he

SUBMITTER: Esserman D 

PROVIDER: S-EPMC11654751 | biostudies-literature | 2024 Jul

REPOSITORIES: biostudies-literature