Objective Visual Acuity Estimates in Amblyopia Are More Accurate With Optotype-Based P300 Than With VEP Measurements.

ABSTRACT:

Purpose

Traditional visual acuity (VA) measurements depend on subjective responses, which can be unreliable, especially with uncooperative participants. Objective measurements with visual evoked potentials (VEP) address this issue but can overestimate VA in amblyopia. This study aims to establish the P300 component of the event-related potential as an objective VA test for amblyopia and compare its performance to subjective (psychophysical) and VEP-based VA estimates.

Methods

Psychophysical, VEP-based, and P300-based VA estimates were obtained for amblyopic and fellow eyes of 18 participants (aged 19-65) in a bicentric study. VEP-based VA was determined from the spatial frequency threshold derived from occipital cortex pattern-pulse responses to check-sizes ranging from 0.04

SUBMITTER: Gopiswaminathan AV 

PROVIDER: S-EPMC11654770 | biostudies-literature | 2024 Dec

REPOSITORIES: biostudies-literature