Hemodynamic phenotypes in chronic kidney disease patients based on linear regression of blood pressure parameters.

ABSTRACT: Classic and non-classic cardiovascular (CV) risk factors accumulate in chronic kidney disease (CKD), contributing to vascular remodeling and hemodynamic abnormalities. This study aimed to determine hemodynamic phenotypes based on linear regression of blood pressure (BP) parameters in stage G3-G4 CKD patients at very high CV risk. 24-h ambulatory BP monitoring (ABPM), carotid-femoral pulse wave velocity (PWV) and central BP were obtained from 52 patients (aged 60 ± 11 years, BMI 30 ± 6 kg/m²) with stage G3-G4 CKD (eGFR 44 ± 12 mL/min./1.73 m²). Linear BP regression coefficients were generated to determine hemodynamic phenotypes using ABPM data. Coexisting hypertension was present in 45 (86%) patients, out of whom 33 (73%) had BP controlled. 24-h mean systolic/diastolic

SUBMITTER: Cierpka-Kmiec K 

PROVIDER: S-EPMC11654849 | biostudies-literature | 2024 Dec

REPOSITORIES: biostudies-literature