Effects of structured exercise training on miRNA expression in previously sedentary individuals.

ABSTRACT:

Introduction

Micro ribonucleic acids (miRNA) respond to acute bouts of vigorous exercise, such as maximal cardiopulmonary exercise tests (CPET), by expressing an anti-atherogenic, anti-inflammatory and hence probably ergogenic profile. However, the impact of long-term engagement in physical exercise on CPET-induced miRNA response in sedentary individuals, with subsequent increased risk for cardiovascular diseases, remains unclear.

Methods

Thirty-four sedentary participants underwent CPET before and after a four-month app-assisted exercise intervention, during which the moderate to vigorous physical activity (MVPA) was increased to over 150 min/week. Capillary blood samples were collected before and after CPET at baseline and after the exercise intervention. Twenty target miR

SUBMITTER: Mayr B 

PROVIDER: S-EPMC11654927 | biostudies-literature | 2024

REPOSITORIES: biostudies-literature