Investigation of the gastric digestion behavior of commercial infant formulae using an <i>in vitro</i> dynamic infant digestion model.

ABSTRACT: The gastric digestion behavior of different commercial Stage 1 infant formulae (for 0-6 months) with different formulation backgrounds was investigated using an in vitro dynamic infant human gastric simulator (iHGS). The microstructural arrangements of the protein and lipid, colloidal stability and protein hydrolysis during digestion were elucidated. During gastric digestion, casein-dominant formulations showed a higher extent of aggregation due to their high proportion of casein micelles that underwent coagulation upon acidification and via the action of pepsin. The extensive protein coagulation/curd formation in casein-dominant infant formulae slowed the rate of protein hydrolysis and resulted in the retention of caseins in the iHGS for longer times. Confocal micrographs showed th

SUBMITTER: Descallar FB 

PROVIDER: S-EPMC11655231 | biostudies-literature | 2024

REPOSITORIES: biostudies-literature