Distinct IgE sensitization profiles in chronic urticaria: a comparative study with classic allergic diseases.

ABSTRACT:

Introduction

Chronic urticaria (CU) is not traditionally classified as an allergic disease, but emerging evidence suggests a link to atopy. The quintessential marker of atopy is IgE sensitization, there is scarce information on the IgE sensitization characteristics of CU.

Methods

To investigate IgE sensitization characteristics in CU, and compare them with classic allergic diseases. We retrospectively analyzed the results of specific IgE (sIgE) and total IgE (tIgE) in CU patients, explored the distribution patterns of these atopic markers in CU, and compared these data with those of atopic dermatitis (AD), allergic rhinitis (AR), asthma (AS), and healthy controls (HC).

Results

1149 patients (396 CU, 411 AD, 101 AR, 139 AS and 102 HC) were included in the study. 33.1%

SUBMITTER: Yang X 

PROVIDER: S-EPMC11655319 | biostudies-literature | 2024

REPOSITORIES: biostudies-literature