Aging of visual word perception is related to decreased segregation within and beyond the word network in the brain.

ABSTRACT:

Introduction

We investigated the neural correlates of cognitive decline in visual word perception from the perspective of intrinsic brain networks.

Methods

A total of 19 healthy older adults and 22 young adults were recruited to participate in two functional magnetic resonance imaging (fMRI) sessions (one resting-state session and one for localizer tasks), along with a visual word perceptual processing task. We examined age-related alterations in resting-state functional connectivity (FC) within the word network, as well as between the word network and other networks. We tested their associations with behavioral performance in word and symbol-form processing.

Results

We found that, compared to young adults, older adults exhibited increased FC between the two word-sele

SUBMITTER: Xue L 

PROVIDER: S-EPMC11655501 | biostudies-literature | 2024

REPOSITORIES: biostudies-literature