Low-cost and label-free blue light cystoscopy through digital staining of white light cystoscopy videos.

ABSTRACT:

Background

Bladder cancer is the 10^th most common malignancy and carries the highest treatment cost among all cancers. The elevated cost stems from its high recurrence rate, which necessitates frequent surveillance. White light cystoscopy (WLC), the standard of care surveillance tool to examine the bladder for lesions, has limited sensitivity for early-stage bladder cancer. Blue light cystoscopy (BLC) utilizes a fluorescent dye to induce contrast in cancerous regions, improving the sensitivity of detection by 43%. Nevertheless, the added equipment cost and lengthy dwell time of the dye limits the availability of BLC.

Methods

Here, we report the first demonstration of digital staining as a promising strategy to convert WLC images collected with standard-of-care cli

SUBMITTER: Chang S 

PROVIDER: S-EPMC11655528 | biostudies-literature | 2024 Dec

REPOSITORIES: biostudies-literature