Implantable silicon neural probes with nanophotonic phased arrays for single-lobe beam steering.

ABSTRACT: In brain activity mapping with optogenetics, patterned illumination is crucial for targeted neural stimulation. However, due to optical scattering in brain tissue, light-emitting implants are needed to bring patterned illumination to deep brain regions. A promising solution is silicon neural probes with integrated nanophotonic circuits that form tailored beam patterns without lenses. Here we propose neural probes with grating-based light emitters that generate a single steerable beam. The light emitters, optimized for blue or amber light, combine end-fire optical phased arrays with slab gratings to suppress higher-order sidelobes. In vivo experiments in mice demonstrated that the optical phased array provided sufficient power for optogenetic stimulation. While beam steering performance in

SUBMITTER: Chen FD 

PROVIDER: S-EPMC11655650 | biostudies-literature | 2024 Dec

REPOSITORIES: biostudies-literature