Identification of a cognitive network with effective connectivity to post-stroke cognitive impairment.

ABSTRACT: Altered connectivity within complex functional networks has been observed in individuals with post-stroke cognitive impairment (PSCI) and during cognitive tasks. This study aimed to identify a cognitive function network that is responsive to cognitive changes during cognitive tasks and also sensitive to PSCI. To explore the network, we analyzed resting-state fMRI data from 20 PSCI patients and task-state fMRI data from 100 unrelated healthy young adults using functional connectivity analysis. We further employed spectral dynamic causal modeling to examine the effective connectivity among the pivotal regions within the network. Our findings revealed a common cognitive network that encompassed the hub regions 231 in the Subcortical network (SC), 70, 199, 242 in the Frontoparietal network (FP

SUBMITTER: Zhang J 

PROVIDER: S-EPMC11655769 | biostudies-literature | 2024 Dec

REPOSITORIES: biostudies-literature