Ionic Dissolution Products of Lithium-, Strontium-, and Boron-Substituted Silicate Glasses Influence the Viability and Proliferation of Adipose Stromal Cells, Fibroblasts, Urothelial and Endothelial Cells.

ABSTRACT: While bioactive glasses (BaGs) have been studied mainly for bone applications, studies have also shown their potential for soft tissue engineering. Incorporating therapeutic ions, such as lithium (Li⁺), strontium (Sr²⁺), and boron (B³⁺) into the BaGs, has been found to promote angiogenesis and wound healing. However, a systematic study on the impact of Li⁺, Sr²⁺, B³⁺, and the other ions in the BaGs, has not been conducted on a wide range of cells. Although the interactions between the BaGs and cells have been studied, it is difficult to compare the results between studies and conclude the impact of BaGs between cell types due to the variability of culture conditions, cells, and materials. We aim to evaluate the dissolution b

SUBMITTER: Lyyra I 

PROVIDER: S-EPMC11656255 | biostudies-literature | 2024 Dec

REPOSITORIES: biostudies-literature