GOLD COPD Exacerbation History Categories and Disease Outcomes.

ABSTRACT:

Importance

Previous exacerbations of chronic obstructive pulmonary disease (ECOPD) are associated with future events. For more than a decade, patients at high risk have been defined as individuals with a history of 2 or more moderate ECOPD, 1 or more severe ECOPD, or both within 12 months, and treatments have been allocated accordingly, but these cutoffs lack validation.

Objectives

To validate ECOPD history categories by the Global Initiative for Chronic Obstructive Lung Disease (GOLD) and explore alternative cutoffs to estimate moderate and severe ECOPD and all-cause mortality in COPD.

Design, setting, and participants

This cohort study analyzed data from patients with COPD in the German COPD and Systemic Consequences-Comorbidities Network (COSYCONET) study. Patients

SUBMITTER: Waeijen-Smit K 

PROVIDER: S-EPMC11656261 | biostudies-literature | 2024 Dec

REPOSITORIES: biostudies-literature