Frontal White Matter Changes and Craving Recovery in Inpatients With Heroin Use Disorder.

ABSTRACT:

Importance

Amidst an unprecedented opioid epidemic, identifying neurobiological correlates of change with medication-assisted treatment of heroin use disorder is imperative. White matter impairments in individuals with heroin use disorder (HUD) have been associated with drug craving, a reliable predictor of treatment outcomes; however, little is known about structural connectivity changes with inpatient treatment and abstinence in individuals with HUD.

Objective

To assess white matter microstructure and associations with drug craving changes with inpatient treatment in individuals with HUD (effects of time and rescan compared with controls).

Design, setting, and participants

This cohort study conducted from December 2020 to September 2022 included individuals recruite

SUBMITTER: Gaudreault PO 

PROVIDER: S-EPMC11656271 | biostudies-literature | 2024 Dec

REPOSITORIES: biostudies-literature