Association of different types of milk with depression and anxiety: a prospective cohort study and Mendelian randomization analysis.

ABSTRACT:

Background

The relationship between different types of milk and depression and anxiety remains unclear, with limited evidence from prospective cohort studies. This study aims to evaluate this relationship using data from the UK Biobank cohort and to explore its potential causality through Mendelian randomization (MR) analysis.

Methods

Cox proportional hazards models were used to assess the association between different milk types and the risk of depression and anxiety among 357,568 UK Biobank participants free of these conditions at baseline. To further explore causality, a 2-sample MR analysis was conducted using data from the FinnGen study.

Results

During a median follow-up period of 13.5 years (interquartile range, 12.6-14.2 years), among 357,568 participants (mean

SUBMITTER: Wu C 

PROVIDER: S-EPMC11656347 | biostudies-literature | 2024

REPOSITORIES: biostudies-literature