Internal State of Vesicles Affects Higher Order State of Vesicle Assembly and Interaction.

ABSTRACT: Dynamic soft matter systems composed of functionalized vesicles and liposomes are typically produced and then manipulated through external means, including the addition of exogenous molecules. In biology, natural cells possess greater autonomy, as their internal states are continuously updated, enabling them to effect higher order properties of the system. Therefore, a conceptual and technical gap exists between the natural and artificial systems. We engineered functionalized vesicles to form multicore aggregates capable of self-assembly due to the presence of complementary ssDNA strands. A dynamic process was then triggered through an exogenously triggered on-demand release of an endogenously produced displacer molecule, resulting in multicore aggregate disassembly. This approach explores

SUBMITTER: Holler S 

PROVIDER: S-EPMC11656350 | biostudies-literature | 2024 Dec

REPOSITORIES: biostudies-literature