Charging and Discharging of Poly(<i>m</i>-aminophenylboronic Acid) Doped with Phytic Acid for Enzyme-Free Real-Time Monitoring of Human Sweat Lactate.

ABSTRACT: In this study, we realized a real-time and enzyme-free measurement of lactate in sweat in the same way as an enzyme-based amperometric method. A conductive polymer, which is based on polyaniline (PANI), was strongly coated on a glassy carbon electrode as a poly m-aminophenylboronic acid (PANI-PBA) membrane by drop-casting, which is a convenient method, owing to adhesive phytic acid (PA) molecules with negative charges included as a dopant. This polymer membrane had a functional structure with PBA in the PANI main chain, which expectedly induced electrical charges upon diol binding to lactate, owing to the formation of deprotonated boronate esters with negative charges. This indicates that PBA served as the self-dopant and as the site of binding to lactate. On the basis of the fundam

SUBMITTER: Kishi R 

PROVIDER: S-EPMC11656369 | biostudies-literature | 2024 Dec

REPOSITORIES: biostudies-literature