Posttraumatic stress disorder and its cross-generational familial relationship with drug use disorder and alcohol use disorder: an extended Swedish adoption study.

ABSTRACT: Objective: Information on how parental risk for posttraumatic stress disorder (PTSD) relates to their children's risk for drug use disorder (DUD) and alcohol use disorder (AUD) is limited. This study is the first to utilize an extended adoption design which can address questions about the degree of, and sources of, cross-generational and cross-disorder transmission of PTSD and substance use disorders.Method: We examined diagnoses using Swedish National registries for parents and their adult offspring (n = 2,194,171, born 1960-1992) from six types of families (intact (1), not lived with biological father (2) or mother (3), step father (4), step mother (5), and adoptive (6)). Parent-child resemblance was assessed by tetrachoric correlation.Results: PTSD and DUD sh

SUBMITTER: Amstadter AB 

PROVIDER: S-EPMC11656752 | biostudies-literature | 2024

REPOSITORIES: biostudies-literature