Fresh whole blood: A feasible alternative in disasters and mass casualty incidents? a systematic review and meta-analysis.

ABSTRACT:

Introduction

While balanced blood component therapy (BCT) is pivotal in trauma patient damage control resuscitation in well-resourced settings, disasters, and mass casualty incidents (MCIs) pose significant challenges, especially in securing sufficient access to blood products. This systematic review and meta-analysis aim to explore the utilization of fresh whole blood (FWB) transfusion as a potential alternative to BCT, informing future research and clinical strategies.

Methods

We searched Pubmed, MEDLINE, Embase, CINAHL, the Cochrane Library and grey literature for articles identifying FWB transfusions, limited to those published in English or French. We evaluated the outcomes of post-FWB transfusion and conducted a meta-analysis comparing overall mortality in patients rec

SUBMITTER: Ripoll-Gallardo A 

PROVIDER: S-EPMC11656982 | biostudies-literature | 2024 Dec

REPOSITORIES: biostudies-literature