Substantiating the Short Burst Duration in Cortical Myoclonus.

ABSTRACT:

Background

Myoclonus is characterized by involuntary, shock-like movements, of which cortical (CM) and non-cortical myoclonus (NCM) are most common. Electrophysiology can help differentiate between these subtypes; however, the diagnostic value of several features is largely unknown.

Objective

This study aims to determine the diagnostic value of the burst duration in distinguishing CM and NCM.

Methods

We manually identified the burst duration of 8 patients with CM, confirmed by electromyography-electroencephalography registration or somatosensory-evoked potentials, and 19 patients with NCM, suspected due to a myoclonus-dystonia phenotype (MYC/DYT-SGCE positive and negative).

Results

The sensitivity and specificity were calculated to assess the diagnostic value.

SUBMITTER: van der Veen S 

PROVIDER: S-EPMC11657038 | biostudies-literature | 2024 Dec

REPOSITORIES: biostudies-literature