Amelioration of Focal Hand Dystonia via Low-Frequency Repetitive Somatosensory Stimulation.

ABSTRACT:

Background

Dystonia presents a growing concern based on evolving prevalence insights. Previous research found that, in cervical dystonia, high-frequency repetitive somatosensory stimulation (RSS; HF-RSS) applied on digital nerves paradoxically diminishes sensorimotor inhibitory mechanisms, whereas low-frequency RSS (LF-RSS) increases them. However, direct testing on affected body parts was not conducted.

Objective

This study aims to investigate whether RSS applied directly to forearm muscles involved in focal hand dystonia can modulate cortical inhibitory mechanisms and clinical symptoms.

Methods

We applied HF-RSS and LF-RSS, the latter either synchronously or asynchronously, on forearm muscles involved in dystonia. Outcome measures included paired-pulse somatosensory

SUBMITTER: Rocchi L 

PROVIDER: S-EPMC11657077 | biostudies-literature | 2024 Dec

REPOSITORIES: biostudies-literature