Global burden of low vision and blindness due to age-related macular degeneration from 1990 to 2021 and projections for 2050.

ABSTRACT:

Background

Age-related macular degeneration (AMD) is a leading cause of blindness and low vision worldwide. This study examines the global burden and trends in AMD-related low vision and blindness from 1990 to 2021, with projections through 2050.

Methods

Data were obtained from the 2021 Global Burden of Disease (GBD 2021) study, covering 204 countries and regions. Key metrics, including the prevalent case numbers, annual disability-adjusted life years (DALYs), age-standardized prevalence rates (ASPR), and age-standardized DALY rates (ASDALYR), specific to low vision and blindness due to AMD, were calculated per 100,000 population. Trend analysis used the estimated annual percentage change (EAPC) method, and K-means clustering identified regions with similar burdens and trend

SUBMITTER: Zhang S 

PROVIDER: S-EPMC11657136 | biostudies-literature | 2024 Dec

REPOSITORIES: biostudies-literature