The diagnostic and prognostic value of heparin-binding protein in cerebrospinal fluid for patients with intracranial infections.

ABSTRACT:

Background

This study aims to evaluate the diagnostic and prognostic value of heparin-binding protein (HBP) in cerebrospinal fluid (CSF) for patients with intracranial infections.

Methods

This study included 211 subjects, of whom 138 were diagnosed with intracranial infections, 20 were patients with non-infectious inflammatory encephalopathies, and 53 controls who were eventually excluded from intracranial infections and inflammatory encephalopathies. The levels of HBP and procalcitonin (PCT) in CSF were detected in the subjects, and the diagnostic value of CSF HBP and PCT for intracranial infections was assessed using the receiver operating characteristic (ROC) curves. In addition, CSF HBP levels in patients with intracranial infections were dynamically monitored on days 1,

SUBMITTER: Ye Y 

PROVIDER: S-EPMC11657152 | biostudies-literature | 2024 Dec

REPOSITORIES: biostudies-literature