Alterations in spontaneous brain activity of maintenance hemodialysis patients with restless legs syndrome: a cross-sectional case-control study.

ABSTRACT:

Objective

Through resting state functional magnetic resonance imaging (rs-fMRI) we evaluate the spontaneous brain activity changes of maintenance hemodialysis (MHD) patients with restless legs syndrome (RSL) and analyzed the imaging features and related mechanisms of RLS in patients with MHD.

Method

We select 27 MHD patients with RLS and 27 patients without RSL matched by age, gender, cognitive function. Both groups underwent neuropsychological tests and MRI scans. MRI data analysis was performed to obtain and compare the amplitude of low-frequency fluctuation (ALFF), fractional amplitude of low-frequency fluctuations (fALFF), and regional homogeneity (ReHo) values, which were mALFF, mfALFF, and mReHo. Clinical data were collected and compared. Differentiated indicators and

SUBMITTER: Wang D 

PROVIDER: S-EPMC11657219 | biostudies-literature | 2024 Dec

REPOSITORIES: biostudies-literature