Long-term survival in patients with univentricular heart: A nationwide, register-based cohort study.

ABSTRACT:

Background

Children with univentricular heart (UVH) have a limited life expectancy without early treatment. Long-term survival in UVH, in an unselected nationwide cohort, is unclear.

Objectives

To determine long-term survival in patients with UVH including non-operated patients compared with a control population in Sweden.

Methods

Patients with UVH born between 1970 and 2017 were identified from the National Registers and were matched for birth year and sex with 10 individuals without congenital heart disease. Follow-up was from birth until death, transplantation, or the end of study. Mortality risk was estimated by Cox proportional regression models and Kaplan-Meier survival analysis.

Results

We included 5075 patients with UVH including 758 (14.9%) patients wi

SUBMITTER: Ozturk AG 

PROVIDER: S-EPMC11657339 | biostudies-literature | 2024 Mar

REPOSITORIES: biostudies-literature