Neutrophil-related indicators as potential peripheral blood biomarkers for the diagnosis of neurosyphilis: a cross-sectional study.

ABSTRACT:

Background

Neurosyphilis (NS) is the most serious complication elicited by the invasion of Treponema pallidum (T. pallidum) into the central nervous system. Identifying the neuro-invasion of T. pallidum as early as possible is important. Looking for indicators with good performance and convenient to operate is in great demand for the diagnosis of NS.

Methods

A cross-sectional study was conducted on 428 human immunodeficiency virus (HIV)-negative syphilis patients who underwent therapy in Shanghai Skin Disease Hospital from April 2022 to June 2023. The syphilis patients were further grouped into non-neurosyphilis (NNS), asymptomatic neurosyphilis (ANS) and symptomatic syphilis (SNS). Laboratory examination results of these patients were analyzed.

Results

Significantly

SUBMITTER: Tang Y 

PROVIDER: S-EPMC11657700 | biostudies-literature | 2024 Dec

REPOSITORIES: biostudies-literature