Increased carotid intima-media thickness and reduced health-related physical fitness in children and adolescents with coarctation of the aorta.

ABSTRACT:

Background

Coarctation of the Aorta (CoA) was assumed to be one of the congenital heart defects not associated with major long-term sequels. Meanwhile, it is known that there are long-term cardiovascular consequences. This study investigates the functional outcome measures in children with CoA.

Methods

77 children (40.3% girls, 13.1 ± 3.3 years) with CoA were examined for their functional outcome measures and compared to healthy controls (CG). Carotid Intima-Media wall thickness (cIMT) was measured by ultrasound of the common carotid artery. In addition, Health-related Physical Fitness (HrPF) was assessed by five tasks of the FITNESSGRAM® and health-related quality of life (HrQoL) was analyzed with a self-report questionnaire (KINDL-R).

Results

After adjustment for ag

SUBMITTER: Remmele J 

PROVIDER: S-EPMC11657730 | biostudies-literature | 2022 Jun

REPOSITORIES: biostudies-literature