The status of insecticide resistance of Anopheles coluzzii on the islands of Sao Tome and Principe, after 20 years of malaria vector control.

ABSTRACT:

Background

Insecticide-based malaria vector control has been implemented on the islands of São Tomé and Príncipe (STP) for more than 20 years. During this period malaria incidence was significantly reduced to pre-elimination levels. While cases remained low since 2015, these have significantly increased in the last year, challenging the commitment of the country to achieve malaria elimination by 2025. To better understand the reasons for increasing malaria cases, levels and underlying mechanisms of insecticide resistance in the local Anopheles coluzzii populations were characterized.

Methods

Mosquito larval collections were performed in the rainy and dry seasons, between 2022 and 2024, in two localities of São Tomé and one locality in Príncipe. Susceptibility to permethrin,

SUBMITTER: Correa M 

PROVIDER: S-EPMC11657776 | biostudies-literature | 2024 Dec

REPOSITORIES: biostudies-literature