Increased epicardial adipose tissue is associated with left ventricular reverse remodeling in dilated cardiomyopathy.

ABSTRACT:

Background

Epicardial adipose tissue (EAT) has been suggested to play paradoxical roles in patients with heart failure. The role of EAT in dilated cardiomyopathy (DCM) patients remains unclear. We aimed to assess the associations between the dynamic changes EAT and left ventricular reverse remodeling (LVRR) in DCM patients based on baseline and follow-up CMR.

Methods

In this prospective study, we consecutive enrolled DCM patients with baseline and follow-up cardiac magnetic resonance (CMR) examinations. All participating patients underwent 1-2 years of guideline-directed medical therapy (GDMT) at follow-up. The EAT was measured as pericardial and epicardial fat thickness, and paracardial fat volume, while the abdominal adiposity was measured in terms of subcutaneous and visc

SUBMITTER: Xu Y 

PROVIDER: S-EPMC11657914 | biostudies-literature | 2024 Dec

REPOSITORIES: biostudies-literature