Associations between serum uric acid and risk of depressive symptoms in East Asian populations.

ABSTRACT:

Background

Despite the fact that observational studies have reported associations between serum uric acid (SUA) and depressive symptoms risk in East Asian populations, there is a lack of evidence demonstrating a causal relationship between them. This study aimed to perform a comprehensive assessment of the relationship between SUA and depressive symptoms.

Methods

This study included two cohort studies and a two-sample Mendelian randomization study. The cross-sectional cohort was derived from the China Health and Retirement Longitudinal Study (CHARLS) wave 3 (in 2015), and the baseline data of participants were extracted from the CHARLS wave 1(in 2011), excluding those with depressive symptoms in 2011 and forming a longitudinal cohort from 2011 to 2015. Logistic multiple regr

SUBMITTER: Yao M 

PROVIDER: S-EPMC11658045 | biostudies-literature | 2024 Dec

REPOSITORIES: biostudies-literature