Off-label use of Lifetech KONAR-MF™ ventricular septal defect occluder for large patent ductus arteriosus closure in <6 ​kg infants.

ABSTRACT:

Background

Device PDA closure is increasingly used in smaller patients. Major safety concerns remain when applied to <6 ​kg infants with large PDA and challenging anatomy. We aimed to report our experience with the new Konar-MF™ ventricular septal defect (VSD) occluder for transcatheter closure of large patent ductus arteriosus (PDA) in infants <6 ​kg.

Methods

Infants <6 ​kg in whom PDA occlusion was attempted using the Konar-MF™ VSD occluder were analyzed to review procedural characteristics and outcomes. Prospective follow-up was achieved until August 2021.

Results

A total of 9 implantations were performed in 7 infants [age: 5.3 ​± ​3.4 (1.7-10.1) months, weight: 4.1 ​± ​0.8 (2.9-5.8) kg]. All PDAs were large and short [minimal ductal diameter: 5.6 ​± ​1.0 (4.5-7.0)

SUBMITTER: Grunenwald Gronier C 

PROVIDER: S-EPMC11658058 | biostudies-literature | 2022 Mar

REPOSITORIES: biostudies-literature