Intraoperative extracorporeal support for lung transplant: a systematic review and network meta-analysis.

ABSTRACT:

Background

In the last decades, veno-arterial extracorporeal membrane oxygenation (V-A ECMO) has been gaining in popularity for intraoperative support during lung transplant (LT), being advocated for routinely use also in uncomplicated cases. Compared to off-pump strategy and, secondarily, to traditional cardiopulmonary bypass (CPB), V-A ECMO seems to offer a better hemodynamic stability and oxygenation, while data regarding blood product transfusions, postoperative recovery, and mortality remain unclear. This systematic review and network meta-analysis aims to evaluate the comparative efficacy and safety of V-A ECMO and CPB as compared to OffPump strategy during LT.

Methods

A comprehensive literature search was conducted across multiple databases (PubMed Embase, Cochrane, S

SUBMITTER: Pettenuzzo T 

PROVIDER: S-EPMC11658095 | biostudies-literature | 2024 Dec

REPOSITORIES: biostudies-literature