Accumulating evidence from meta-analyses of prognostic studies on oral cancer: towards biomarker-driven patient selection.

ABSTRACT:

Background

Many histopathologic prognostic markers, identified by routine hematoxylin and eosin (HE) staining, have been proposed for predicting the survival of patients with oral squamous cell carcinoma (OSCC). Subsequently, several meta-analyses have been conducted on these prognostic markers. We sought to analyze the accumulated evidence from these meta-analyses.

Methods

An electronic database search of PubMed, Scopus, Ovid Medline, Web of Science, and Cochrane Library was conducted to retrieve all meta-analysis articles published on histopathologic prognostic markers of OSCC. The risk of bias of the included studies was analyzed using the Risk of Bias in Systematic Reviews (ROBIS) tool. The synthesis of the results was conducted following the guidelines of Preferred Repo

SUBMITTER: Almangush A 

PROVIDER: S-EPMC11658108 | biostudies-literature | 2024 Dec

REPOSITORIES: biostudies-literature