Comparison of methods to normalize urine output in critically ill patients: a multicenter cohort study.

ABSTRACT:

Background

Oliguria diagnosis includes the normalization of urine output (UO) by body weight. However, the rational and the method to apply to normalize UO to body weight are unclear. We aimed to explore the impact of the method applied to normalize UO on oliguria incidence and association with outcomes.

Methods

We included all adult patients admitted to a Swiss (derivation cohort) and a US (MIMIC-IV database, validation cohort) ICU, except those on maintenance hemodialysis, who declined consent or had < 6 consecutive UO measurements. Among a panel of candidate variables (ideal body weight, body mass index, body surface area and adjusted body weight), we identified the best predictor for UO (i.e. the variable that was most closely associated with mean UO during ICU stay). We

SUBMITTER: Monard C 

PROVIDER: S-EPMC11658224 | biostudies-literature | 2024 Dec

REPOSITORIES: biostudies-literature