In silico prediction of pathogen's pandemic potential using the viral trait assessment for pandemics (ViTAP) model.

ABSTRACT: Our world is ever evolving and interconnected, creating constant opportunities for disease outbreaks and pandemics to occur, making pandemic preparedness and pathogen management crucial for global health security. Early pathogen identification and intervention play a key role in mitigating the impacts of disease outbreaks. In this perspective, we present the Viral Trait Assessment for Pandemics (ViTAP) model to aid in the early identification of high-risk viruses that have pandemic potential, which incorporates lessons from past pandemics, including which key viral characteristics are important such as genetic makeup, transmission modes, mutation rates, and symptom severity. This model serves as the foundation for the development of powerful, quantitative tools for the early prediction of

SUBMITTER: Jones CH 

PROVIDER: S-EPMC11658415 | biostudies-literature | 2024 Dec

REPOSITORIES: biostudies-literature