Strategic vaccination responses to Chikungunya outbreaks in Rome: Insights from a dynamic transmission model.

ABSTRACT:

Background

Chikungunya virus (CHIKV) outbreaks, driven by the expanding habitat of the Aedes albopictus mosquito and global climate change, pose a significant threat to public health. Our study evaluates the effectiveness of emergency vaccination using a dynamic disease transmission model for a potential large-scale outbreak in Rome, Italy.

Methods

The model incorporates a susceptible-exposed-infected-recovered (SEIR) framework for human and mosquito populations, taking into account temperature-dependent mosquito lifecycle dynamics, human-mosquito interactions, and various vaccination scenarios.

Findings

Results indicate that emergency vaccination could significantly mitigate the impact of a CHIKV outbreak. Without vaccination, an outbreak is estimated to infect up to

SUBMITTER: Sloof AC 

PROVIDER: S-EPMC11658691 | biostudies-literature | 2024 Dec

REPOSITORIES: biostudies-literature