<i>Polygonum multiflorum</i> Extracellular Vesicle-Like Nanovesicle for Skin Photoaging Therapy.

ABSTRACT: Ultraviolet (UV) irradiation leads to the degradation of the extracellular matrix and collagen, thereby accelerating skin aging and imposing substantial psychological burden on patients. Current anti-aging strategies are limited and often associated with high costs or strong side effects. Plant-derived extracellular vesicle-like nanovesicles, with advantages such as natural availability and cost-effectiveness, show potential in anti-aging interventions. This study extracted extracellular vesicle-like nanovesicle from Polygonum multiflorum (PMELNVs) and systematically investigated their composition and metabolic pathways, further examining their efficacy and underlying mechanisms in combating photoaging. Results revealed the excellent antioxidative properties of PMELNVs, alleviating

SUBMITTER: He J 

PROVIDER: S-EPMC11658808 | biostudies-literature | 2024

REPOSITORIES: biostudies-literature